I use the preamp section of active DI boxes to get the proper gain staging to cleanly drive a mixer. It can be as simple and inexpensive as a Behringer ADI21. The pickups and electronics in some instruments don't have the power to drive an amp or board. Also, active preamp DI boxes have XLR outputs to drive longer distances through lower impedance, balanced lines. How long of an instrument cable are you using?
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