I use the clean setting most of the time with tone towards the middle but I move the gain a lot depending upon single coil or humbucker guitar. Mine's almost always used with tablet, phone or computer plugged in so I use the right side aux and input adjustments more than the master and gain knobs. Finally, just a little bit of spring reverb setting.
More and more it's almost always used with the Trio+, boost pedal and tuner pedal. The Trio+ is just a great item. The boost pedal aids the move between single coil and humbucker. It has cut my changing any amp settings for the guitar.
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