For the most part, it doesn't matter, as the Audient ID14 is compatible with either computer and compatible with either's current operating systems (Windows 10 or MacOS Mojave).
A few thoughts:
1) Cost favors a PC.
2) Most current DAWs favor either, although some DAWs only work on one or the other (e.g., Logic only for Mac, Cakewalk/Sonar for PC, Reaper and ProTools for either).
3) Each DAW uses software plugins, the format of which may be different for one DAW compared to another, e.g., VST/VST2, AAX, AudioUnits. Nearly all plugins come in each of these formats.
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