Nope, not in my experience. You may need to change the relief but we're not talking dramatic differences here.
I've used them on my J45 and my Eastman E10 00, both of which are shorter scaled guitars. As everyone is different, the usual disclaimers apply.
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Nothing bothers me unless I let it.
Martin D18
Gibson J45
Gibson J15
Fender Copperburst Telecaster
Squier CV 50 Stratocaster
Squier CV 50 Telecaster
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