You can definitely use any effects you want with it. Play with your Boss Distortion and see if you can get a sound you like with that. If you have the ME70 (I know you mentioned it), try that too. I used to do a lot with an Ovation Balladeer, a full pedalboard, and an electric guitar amp. You can get some unique and whacky sounds using a setup like that. Experiment! Have fun! Definitely post if you find something cool and you want to share