I have both sizes and can move back and forth with relative ease, but there is a distinct difference. The smaller nut requires a little more accuracy to keep from buzzing adjacent strings, but it also means smaller stretches when it counts. I can't say that I like either one better; it depends on what I'm playing.
Also, as others have noted, neck depth and profile also figure into it. I generally favor slim necks, especially if I'm thumbing the 6th string.
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Chris
We all do better when we all do better.
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