Hi LuisD...
Yes, too frequent ''cleaning'' if aggressive could affect the guitar finish or condition.
Like most who posted here, I only wipe down the strings after every time I play (to extend their life and usefulness). I wipe the body down occasionally too.
If there is a patch of skin oil - like where my forearm crossed the lower bout on my picking hand - and I feel inclined to clean it off (or need to shoot pics of the guitar) then I use a few drops of Naptha (otherwise known as lighter fluid), on a rag and work it off.
It will not damage most guitars (unless you have a varnished hand rubbed finish) and Naptha evaporates without leaving residue. I buy it as lighter fluid for $.99 at the drug store, and luthiers buy it by the gallon in cans. I always read the label to make sure the only ingredient in it is Naptha.
Hope this helps...
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