Hello there... I just came back into the house about two hours ago from being out in the garage with two of my music buddies. I used my T5 tonight running it straight into the PA (Yamaha EMX312sc). When reading Taylorplayer's post about the settings, I looked at the PA head that I carried back in tonight. I have the Highs set at 12, the Mids set at 8/9 and the Bass at 2. Tonight I played mostly on setting 1 on the T5 tweaking the tones I wanted with the guitar controls. I did use Position 5 a few songs adjusting the treble and bass controls getting the sound I wanted.
Sometimes I will use a solid state modeling amp (do not have a tube available now) and set it to the Fender setting and get clean sounds. I use the ABY box switching between the PA and amp, or running them at the same time. It works for me.
Enjoy your T5