The sound of all the pickups (and some awful piezos) will be affected by the impedence of the preamp they are plugged into. Different DI boxes and different stomp boxes can change the tone. A magnetic pickup straight into the line in of a PA usually sounds way more thin and sissified than it will with a proper preamp.
They cost $120, but an E-H Hum debugger is my favorite preamp, plus it kills 60 cycle hum actively (Same principle as noise cancelling headphones.)
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