My first good electric was a '74 Les Paul that I bought used in '77 and it was my main squeeze for years. I still have it and use it on sessions.
I've since added another one that is lighter (7.8 lbs) as well.
When you need a full-bodied sound, the Les Paul is just it. I've tried a bunch of others, but there is a certain girth that a Les Paul has naturally.
Each guitar has its thing - the Tele is great for brighter, articulate work, as is the SG, the Strat adds the ability to wiggle a chord with the tailpiece, the ES-335 is sweeter and more plaintive as a lead instrument, but the LP has a certain gut and power to it. You just have to figure it out.
Bob